USP Chromatographic Columns

The Chromatographic Columns online database is a compilation of the chromatographic columns used to validate the chromatographic procedures in USP-NF, Pharmacopeial Forum, Revision Bulletins, and Interim Revision Announcements. It provides a cumulative listing of columns referenced in gas- and liquid-chromatographic methods related to revisions made to USP-NF since January 1980.

Chromatographic Columns Contents

Chromatographic Columns provides the following column data:

Issue of PF in which a column was first referenced
Corresponding packing, GC phase, or support (L, G, or S) designations
Type of test employing the chromatographic method
Alternative columns, when this information is available
Brand names
Manufacturers

How Chromatographic Columns Assists the User

Save valuable time spent searching for the right columns to use in testing
Track columns used in methods that have progressed from "revision" to "official" status
Find brand names and manufacturers
Locate alternative columns that may be used

Designation

The designation for a new column will receive a number ONLY when the text referring to this column becomes official, whether in a Supplement, in the next USP-NF, or in a Revision Bulletin or Interim Revision Announcement. During the proposal period in Pharmacopeial Forum, the new chromatographic column will be identified in the database by "L##", "G##", or "S##" followed by the monograph title and the column brand name in parentheses. No numbers will be assigned to the column designations during the proposal period. See the example below.

Example:
L## (Lanatoprost, Chiracel OD-R)-Cellulose tris(3,5-dimethylphenylcarbamate) coated on 10-µm silica gel particles.

In the actual text of the monograph or general chapter that requires the new column, that column will be designated as "L##", "G##" or "S##" and will appear with the reference "(see Reagents, Indicators, and Solutions, Chromatographic Columns)".